Olga Korczeniewska

My research interests include investigating molecular mechanisms contributing to neuropathic pain development and maintenance as well as sex-dimorphism of pain. I collaborate with a team of researchers to investigate the predictive value of exercise-induced hypoalgesia profile in rats on pain intensity inflicted by peripheral nerve injury. We use animal models of neuropathic pain to identify gene expression changes associated with neuropathic pain development and maintenance in male and female rats with the long-term goal of identifying molecular targets for mechanism based and more effective treatments for neuropathic pain.

BA, Computer Science, Rutgers University/New Jersey Institute of Technology

PhD, Biomedical Sciences, Rutgers University

1. Molecular mechanisms underlying neuropathic pain development
2. Molecular mechanisms contributing to sex-dimorphism of neuropathic pain
3. Designer Receptors Exclusively Activated by Designer Drugs in the management of trigeminal neuropathic pain

1. Post-endodontic pain: a practical approach to diagnosis and management. Kohli D, Falcon C, Rider G, Benoliel R, Khan J, Korczeniewska OA. Quintessence Int. 2021 Mar 10;0(0):0. doi: 10.3290/j.qi.b1044039. Online ahead of print. PMID: 33688715
2. Diagnosis and management of persistent posttraumatic trigeminal neuropathic pain secondary to implant therapy: A review. Kohli D, Katzmann G, Benoliel R, Korczeniewska OA. J Am Dent Assoc. 2020 Dec 5:S0002-8177(20)30601-2. doi: 10.1016/j.adaj.2020.08.017. Online ahead of print. PMID: 33293028 No abstract available.
3. Molecular mechanisms of painful traumatic trigeminal neuropathy-Evidence from animal research and clinical correlates. Korczeniewska OA, Khan J, Eliav E, Benoliel R. J Oral Pathol Med. 2020 Jul;49(6):580-589. doi: 10.1111/jop.13078. Epub 2020 Jul 4. PMID: 32557871 Review.
4. Differential gene expression changes in the dorsal root versus trigeminal ganglia following peripheral nerve injury in rats. Korczeniewska OA, Katzmann Rider G, Gajra S, Narra V, Ramavajla V, Chang YJ, Tao Y, Soteropoulos P, Husain S, Khan J, Eliav E, Benoliel R. Eur J Pain. 2020 May;24(5):967-982. doi: 10.1002/ejp.1546. Epub 2020 Mar 13. PMID: 32100907
5. The Effect of Nonstrenuous Aerobic Exercise in Patients with Chronic Masticatory Myalgia. Nasri-Heir C, Patil AG, Korczeniewska OA, Zusman T, Khan J, Heir G, Benoliel R, Eliav E. J Oral Facial Pain Headache. 2019 Spring;33(2):143–152. doi: 10.11607/ofph.2342. Epub 2019 Feb 6. PMID: 30726861
6. Age and gender differences in mechanically induced intraoral temporal summation and conditioned pain modulation in healthy subjects. Khan J, Korczeniewska O, Benoliel R, Kalladka M, Eliav E, Nasri-Heir C. Oral Surg Oral Med Oral Pathol Oral Radiol. 2018 Aug;126(2):134-141. doi: 10.1016/j.oooo.2018.03.021. Epub 2018 Apr 13. PMID: 29857979
7. Differential gene expression in trigeminal ganglia of male and female rats following chronic constriction of the infraorbital nerve. Korczeniewska OA, Husain S, Khan J, Eliav E, Soteropoulos P, Benoliel R. Eur J Pain. 2018 May;22(5):875-888. doi: 10.1002/ejp.1174. Epub 2018 Jan 19. PMID: 29350446
8. Primary burning mouth syndrome: Literature review and preliminary findings suggesting possible association with pain modulation. Nasri-Heir C, Shigdar D, Alnaas D, Korczeniewska OA, Eliav R, Heir GM. Quintessence Int. 2017 Dec 20;49(1):49-60. doi: 10.3290/j.qi.a39403. Epub 2017 Nov 30. PMID: 29192294
9. Interleukin-8 levels in rat models of nerve damage and neuropathic pain. Khan J, Hassun H, Zusman T, Korczeniewska O, Eliav E. Neurosci Lett. 2017 Sep 14;657:106-112. doi: 10.1016/j.neulet.2017.07.049. Epub 2017 Aug 5. PMID: 28789985
10. Effects of Sex and Stress on Trigeminal Neuropathic Pain-Like Behavior in Rats. Korczeniewska OA, Khan J, Tao Y, Eliav E, Benoliel R. J Oral Facial Pain Headache. 2017 Fall;31(4):381-397. doi: 10.11607/ofph.1807. PMID: 29073664
11. Altered pain modulation in patients with persistent postendodontic pain. Nasri-Heir C, Khan J, Benoliel R, Feng C, Yarnitsky D, Kuo F, Hirschberg C, Hartwell G, Huang CY, Heir G, Korczeniewska O, Diehl SR, Eliav E. Pain. 2015 Oct;156(10):2032-2041. doi: 10.1097/j.pain.0000000000000265. PMID: 26098442 Free PMC article. Clinical Trial.
12. Interleukin-10 levels in rat models of nerve damage and neuropathic pain. Khan J, Ramadan K, Korczeniewska O, Anwer MM, Benoliel R, Eliav E. Neurosci Lett. 2015 Apr 10;592:99-106. doi: 10.1016/j.neulet.2015.03.001. Epub 2015 Mar 7. PMID: 25757362
13. Exercise-induced hypoalgesia profile in rats predicts neuropathic pain intensity induced by sciatic nerve constriction injury. Khan J, Benavent V, Korczeniewska OA, Benoliel R, Eliav E. J Pain. 2014 Nov;15(11):1179-1189. doi: 10.1016/j.jpain.2014.08.012. Epub 2014 Sep 16. PMID: 25218554